Pharmacology & ToxicologybioRxivPreprint
JHU-2545 Selectively Shields Salivary Glands and Kidneys during PSMA-Targeted Radiotherapy
Michael T. Nedelcovych, Ranjeet P. Dash, Ying Wu…·Barbara S. Slusher
This paper describes the development of JHU-2545, a prodrug that selectively shields salivary glands and kidneys from PSMA-targeted radiotherapy, improving safety without affecting tumor uptake.