Synthetic BiologyMolecular Therapy OncologyPeer-reviewed
CRISPR-Cas13d-mediated targeting of a context-specific essential gene enables selective elimination of uveal melanoma
Daniel Stauber, Lucas Sosnick, Yitong Ma…·Lei S. Qi
The paper identifies RASGRP3 as a context-specific essential gene in uveal melanoma and develops a CRISPR-Cas13d RNA-targeting therapeutic that selectively eliminates uveal melanoma cells.
2 citations