Author

Dario Rüegg

ETH Zurich

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Microbiology· 1

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Approach:statistical model· 1

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Berit SiedentopiD· 1 shared Hélène ChabasiD· 1 shared Sebastian BonhoefferiD· 1 shared

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MicrobiologyProceedings of the Royal Society B Biological SciencesPeer-reviewedJan 23, 2024

My host's enemy is my enemy: plasmids carrying CRISPR-Cas as a defence against phages

Berit Siedentop, Dario Rüegg, Sebastian Bonhoeffer, Hélène Chabas

The paper develops a stochastic model to evaluate CRISPR-Cas plasmid-based anti-phage protection, showing it is robust except under specific parameter conditions where segregation loss enables phage outbreaks.

11 citations

statistical model

𝕏 PostBluesky