Author

Darshan V. Trivedi

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Biology Disciplines

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Biochemistry· 1

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Arjun S. Adhikari· 1 shared James A. SpudichiD· 1 shared Kathleen M. RuppeliD· 1 shared Makenna M. Morck· 1 shared Saswata S. Sarkar· 1 shared Shaik N. Pasha· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

Arjun S. Adhikari

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintFeb 7, 2019

The molecular basis of hypercontractility caused by the hypertrophic cardiomyopathy mutations R403Q and R663H

Saswata S. Sarkar, Darshan V. Trivedi, Makenna M. Morck…·James A. Spudich

This study investigates how HCM mutations R403Q and R663H in myosin cause hypercontractility by increasing functionally-accessible myosin heads and affecting MyBP-C binding.

DOI 10.1101/543413

humanexperimental assay

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