Cell BiologybioRxiv
Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions.
Vinay Swaminathan, Joseph Mathew Kalappurakkal, Shalin B. Mehta…·Clare M Waterman
The paper shows that actin retrograde flow aligns and orients ligand-bound integrins in focal adhesions through force-induced structural changes.
DOI 10.1073/pnas.1701136114