Author

David H. Nguyen

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Bioinformatics· 1

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Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Assay:imaging· 1 Approach:statistical model· 1

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Jennifer M. RosenbluthiD· 1 shared Michael Bruck· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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Jennifer M. RosenbluthORCID

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1 paper

Recent·Most cited

BioinformaticsJournal of Visualized ExperimentsPeer-reviewedJul 21, 2026

A Shape Analysis Algorithm Quantifies Spatial Morphology and Context of 2D to 3D Cell Culture for Novel Quantitation of Phenotypes

David H. Nguyen, Michael Bruck, Jennifer M. Rosenbluth

This paper introduces a shape analysis algorithm, LCPC, to quantify spatial morphology and context in 2D and 3D cell cultures, capturing features like chirality that traditional metrics miss.

DOI 10.3791/71066

imagingstatistical model

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