Author

David Horn

Primary ORCID profile (0000-0001-5173-9284 · 11 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

David HorniD11 papers · University of Dundee

Biology Disciplines

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Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Organism:multiple species· 1

Frequent Co-Authors

Abdul Samad· 1 shared Benny Chor· 1 shared Farnaz ZahedifardiD· 1 shared Mark C. FieldiD· 1 shared Martin ZoltneriD· 1 shared Ning Zhang· 1 shared Richard J. Wall· 1 shared Sagi Shporer· 1 shared

Activity by Year

2015-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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1 shared paperCell Biology

Abdul Samad

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2 papers

Recent·Most cited

Targeted protein degradation of the CPSF complex by benzoxaboroles through sumoylation

Ning Zhang, Abdul Samad, Farnaz Zahedifard, Richard J. Wall, David Horn, Martin Zoltner, Mark C. Field

This study identifies CPSF3 as a target of benzoxaboroles in trypanosomatids, showing that BoBs induce sumoylation-dependent degradation of CPSF complex members, leading to reduced mRNA levels.

bioRxiv · Mar 11, 2024 · PreprintCell Biology

Chromosomal Inversion Symmetry: Generalized Chargaff Rules

Sagi Shporer, Benny Chor, David Horn

The paper generalizes Chargaff's second rule to k-mers, showing inversion symmetry in chromosomes across species and demonstrating its evolutionary origin through chromosomal inversions.

bioRxiv · Jan 14, 2015 · PreprintGenomics