BiochemistryAnalytical ChemistryPeer-reviewed
Integrated Multi-Omics Enabled by Sequential Extraction for Comprehensive Molecular Profiling of Small Extracellular Vesicles
Andrew J. Perciaccante, Holden T. Rogers, Yanlong Zhu…·Ying Ge
This paper presents a multi-omics platform for simultaneous lipid, metabolite, and protein analysis of sEVs using sequential extraction and mass spectrometry, achieving deep and reproducible characterization with 10 million sEVs.
DOI 10.1021/acs.analchem.6c01280