Andrew J. Perciaccante

This study uses proteomics to show that aging, sex, and region affect lung ECM remodeling, with age being the main factor and females showing more pronounced changes.

This paper presents a multi-omics platform for simultaneous lipid, metabolite, and protein analysis of sEVs using sequential extraction and mass spectrometry, achieving deep and reproducible characterization with 10 million sEVs.

This study identifies SAMT-247's off-target effects on zinc-coordinating proteins in immune cells, showing increased metabolic and immune responses in stimulated THP-1 cells.

This study uses quantitative proteomics to identify ECM protein alterations in end-stage ICM, revealing key upregulated components and pathways involved in adverse remodeling.

The paper identifies ssTnI overexpression as enhancing cardiomyocyte proliferation and regenerative capacity post-MI through metabolic shifts.