Author

David Lowe

AstraZeneca (United Kingdom)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

Andres N. FernandeziD· 1 shared Anindya RoyiD· 1 shared Ashley ChangiD· 1 shared Asim K. BeraiD· 1 shared Audrey OlshefskyiD· 1 shared Cameron M. ChowiD· 1 shared Catherine L. Overed-SayeriD· 1 shared David A. BakeriD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Andres N. FernandezORCID

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1 paper

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedSep 13, 2023

De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8

Anindya Roy, Lei Shi, Ashley Chang…·David A. Baker

This paper designs highly selective miniprotein inhibitors for integrins αvβ6 and αvβ8 with picomolar affinity and therapeutic potential in a mouse fibrosis model.

58 citationstop 1%

mouseprotein structure

𝕏 PostBluesky