Molecular BiologybioRxivPreprint
The RNA-binding protein Puf5 buffers mRNA levels against chromatin-mediated changes in nascent transcription
David Z. Kochan, Julia S. P. Mawer, Kiril Tishinov…·Peter Tessarz
The paper shows that Puf5 stabilizes transcripts to buffer mRNA levels against changes in nascent transcription mediated by H3K56A mutation, preventing synthetic lethality.
DOI 10.1101/2020.08.13.249912