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Debashish Sahoo

Moores Cancer Center

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Approach:statistical model· 1

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Lee SwansoniD· 1 shared Michael GetziD· 1 shared Padmini RangamaniiD· 1 shared Pradipta GhoshiD· 1 shared

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Systems BiologybioRxivPreprintJul 13, 2018

Guanine-nucleotide Exchange Modulator, GIV/Girdin, Serves as a Tunable Valve for Growth Factor-Stimulated Cyclic AMP Signals

Michael Getz, Lee Swanson, Debashish Sahoo…·Padmini Rangamani

The paper presents a network-based model of GIV/Girdin-dependent cAMP signaling, revealing its role as a tunable control valve distinct from GPCRs and PDEs.

2 citations

statistical model

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