BioinformaticsbioRxivPreprint
Cellpin enables reference-based imputation and denoising of spatial transcriptomes
Philipp Putze, Daniele Lucarelli, Deelaka Wellappili…·Dieter Saur
Cellpin imputes and denoises spatial transcriptomes using a variational autoencoder trained on single-cell RNA-seq, outperforming existing methods without requiring cross-modality alignment.
DOI 10.64898/2026.06.02.729566