Molecular BiologyeLifePeer-reviewed
Spatial patterning of P granules by RNA-induced phase separation of the intrinsically-disordered protein MEG-3
Jarrett Smith, Deepika Calidas, Helen Schmidt…·Geraldine Seydoux
The paper shows that MEG-3, an intrinsically disordered protein, forms P granules in C. elegans zygotes through RNA-induced phase separation, and that MEX-5 suppresses this process in the anterior cytoplasm.
DOI 10.7554/elife.21337