Nicole L. Rosin

This study shows that SCN1A haploinsufficiency disrupts neural progenitor networks and accelerates neurogenesis in human Dravet syndrome forebrain assembloids, leading to altered corticogenesis and circuit hyperexcitability.

This study shows that B cell-induced lymph node stromal remodeling impairs neutrophil response to secondary Staphylococcus aureus infection by disrupting the FRC-conduit network.

This study identifies APOL7C as a pore-forming protein that facilitates phagosomal rupture and antigen cross-presentation by cDC1s.

This study shows primary cilia modulate astrocyte diversity and function through Shh signaling and intracellular balance, affecting neuronal development and behavior.

This paper constructs a single-cell transcriptomics atlas for the parasitic nematode Heligmosomoides bakeri using orthologs from C. elegans to compare cell types and biological processes.

The paper uses single-cell RNA sequencing to identify fibroblast subtypes in zebrafish and shows that perivascular/interstitial fibroblasts regenerate tenocytes via Hedgehog signaling.

This study identifies nkx3.1-expressing precursors in zebrafish that differentiate into brain pericytes and shows their regulation by cxcl12b-Cxcr4 signaling.

This paper presents a method for snRNAseq from frozen human skeletal muscle, enabling analysis of cell types despite tissue degradation and pathological changes.