BiochemistrybioRxivPreprint
Acetylation-Primed SUMOylation Drives RORβ Turnover via a p300-SIRT1 Regulatory Axis
Timothy R. O’Leary, Denis Shutin, Nadeska I. Montalvan…·Mi Ra Chang
This paper identifies a post-translational regulatory axis involving p300 and SIRT1 that controls RORβ stability and transcriptional activity through acetylation and SUMOylation.
DOI 10.1101/2024.10.30.621067