Author

E. Akalestou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Animal Behavior & Cognition· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:behavioral assay· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

G. A. Rutter· 3 shared I. Leclerc· 3 shared L. Lopez-Noriega· 3 shared A. Alamshah· 1 shared A. F. Rodriguez· 1 shared A. Miras· 1 shared C. Viscomi· 1 shared E. Georgiadou· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersPhysiology

G. A. Rutter

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Bariatric surgery normalizes circulating glucocorticoid levels and lowers glucocorticoid action tissue-selectively in mice

E. Akalestou, L. Lopez-Noriega, I. Christakis, A. Miras, I. Leclerc, G. A. Rutter

This study shows bariatric surgery lowers glucocorticoid levels and reduces tissue-specific glucocorticoid activity in mice, improving insulin sensitivity without significant weight loss.

bioRxiv · Jul 23, 2020 · PreprintPhysiology

Intravital imaging of islet Ca2+ dynamics reveals enhanced β cell connectivity after bariatric surgery in mice

E. Akalestou, K. Suba, L. Lopez-Noriega, E. Georgiadou, P. Chabosseau, I. Leclerc, V. Salem, G. A. Rutter

This study uses intravital imaging to show that bariatric surgery enhances β cell connectivity and Ca2+ dynamics in mice, leading to improved glucose tolerance and insulin secretion.

bioRxiv · May 5, 2020Cell Biology

Vertical sleeve gastrectomy lowers kidney SGLT2 expression in the mouse

E. Akalestou, L. Lopez-Noriega, I. Leclerc, G. A. Rutter

This study shows that vertical sleeve gastrectomy reduces kidney SGLT2 expression in mice, which may explain improved glucose tolerance after bariatric surgery.

bioRxiv · Aug 21, 2019 · PreprintPhysiology

The homeostatic dynamics of feeding behaviour identify novel mechanisms of anorectic agents

T. M. McGrath, E. Spreckley, A. F. Rodriguez, C. Viscomi, A. Alamshah, E. Akalestou, K. G. Murphy, N. S. Jones

This study develops a stochastic model of rodent feeding behavior to analyze how anorectic agents affect feeding patterns and reveals that these agents do not mimic satiety.

bioRxiv · May 9, 2019Animal Behavior & Cognition