Author

K. Suba

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 4 Organism:mouse· 4 Approach:experimental assay· 3 Assay:imaging· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

V. Salem· 4 shared G. A. Rutter· 3 shared B. Hansen· 2 shared B. Jones· 2 shared A. Benrick· 1 shared A. Kim· 1 shared A. M. Alonso· 1 shared A. Roberts· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersCell Biology

V. Salem

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Intra-islet glucagon signalling regulates pulsatile insulin secretion and glucose homeostasis

K. Suba, Y. Patel, A. M. Alonso, A. Roberts, B. Hansen, M. Norton, J. Shrewsbury, R. Kwok, V. Kalogianni, S. Chen, X. Liu, G. A. Rutter, B. Jones, J. Minnion, B. M. Owen, , V. Salem

This study shows that loss of intra-islet glucagon receptor signaling impairs glucose tolerance and insulin pulsatility in mice, suggesting glucagonergic agents could restore insulin pulsatility in T2D.

bioRxiv · Sep 1, 2022 · PreprintPhysiology

Divergent acute versus prolonged pharmacological GLP-1R responses in adult beta cell-selective β-arrestin 2 knockout mice

S. Bitsi, Y. Manchanda, L. ElEid, N. Mohamed, B. Hansen, K. Suba, G. A. Rutter, V. Salem, B. Jones, A. Tomas

This study examines GLP-1R responses in beta cell-specific β-arrestin 2 knockout mice, finding acute deficits and prolonged effects with certain agonists.

bioRxiv · Apr 21, 2022 · PreprintCell Biology

Intravital imaging of islet Ca2+ dynamics reveals enhanced β cell connectivity after bariatric surgery in mice

E. Akalestou, K. Suba, L. Lopez-Noriega, E. Georgiadou, P. Chabosseau, I. Leclerc, V. Salem, G. A. Rutter

This study uses intravital imaging to show that bariatric surgery enhances β cell connectivity and Ca2+ dynamics in mice, leading to improved glucose tolerance and insulin secretion.

bioRxiv · May 5, 2020Cell Biology

Arginine-vasopressin mediates counter-regulatory glucagon release and is diminished in type 1 diabetes

A. Kim, J. G. Knudsen, J. C. Madara, A. Benrick, T. Hill, L. Abdul Kadir, J. A. Kellard, L. Mellander, C. Miranda, H. Lin, T. James, K. Suba, A. Spigelman, Y. Wu, P. MacDonald, , L. Briant

This study identifies arginine-vasopressin as a systemic regulator of glucagon secretion, showing its role in counter-regulatory responses to hypoglycemia and its impairment in type 1 diabetes.

bioRxiv · Jan 30, 2020Cell Biology