Activation of hTREK-1 by polyunsaturated fatty acids does not only involve membrane tension
E. Bechard, E. Arel, J. Bride, J. Louradour, X. Bussy, A. Elloumi, C. Vigor, P. SOULE, C. Oger, J.-M. Galano, T. Durand, J.-Y. Le Guennec, H. moha-ou-maati, M. Demion
This study investigates how polyunsaturated fatty acids (PUFAs) activate TREK-1 channels, finding that activation occurs through a two-step mechanism not solely dependent on membrane tension or fluidity.
bioRxiv · Aug 1, 2022 · PreprintBiophysics