T. Durand

Proteome-Wide Bioinformatic Annotation and Functional Validation of the Monotopic Phosphoglycosyl Transferase Superfamily

The paper identifies and validates substrate specificity of bacterial monotopic phosphoglycosyl transferases using bioinformatics and in vitro assays, supporting inhibitor discovery for antibiotic development.

Non-enzymatic oxylipin production in a mudflat microphytobenthic biofilm: evidence of a diatom response to light

This study investigates non-enzymatic oxylipin production in a mudflat microphytobenthic biofilm under varying light irradiances, finding increased isoprostane levels under high light conditions.

Co-infection with two iflaviruses (deformed wing virus and sacbrood virus) affects viral and immune dynamics and synergistically increases honey bee mortality

This study co-inoculates honey bees with deformed wing virus and sacbrood virus to show synergistic effects on viral replication and immune responses, increasing mortality.

Thermal fluctuations independently modulate physiological plasticity and the dynamics of the gut microbiome in a tropical rocky shore oyster

This study shows that thermal fluctuations independently affect the biochemical responses and microbiome dynamics of oysters in high-supratidal zones.

Activation of hTREK-1 by polyunsaturated fatty acids does not only involve membrane tension

This study investigates how polyunsaturated fatty acids (PUFAs) activate TREK-1 channels, finding that activation occurs through a two-step mechanism not solely dependent on membrane tension or fluidity.

The gut parasite Nosema ceranae impairs olfactory learning in bumblebees

This study shows that exposure to Nosema ceranae reduces olfactory learning and memory in bumblebees across different learning tasks.

Artificial diets modulate infection rates of Nosema ceranae in bumblebees

This study develops an experimental protocol to infect bumblebees with Nosema ceranae and finds that diet composition significantly affects parasite prevalence and survival.

Hepatitis C virus regulates its replication by maturing miR-122 through Akt-dependent phosphorylation of KSRP

This study identifies Akt-dependent phosphorylation of KSRP as essential for miR-122 maturation, which HCV exploits to enhance its replication.

Oxidized products of α-linolenic acid negatively regulate cellular survival and motility of breast cancer cells

This study evaluates plant-derived oxidized α-linolenic acid products for their cytotoxic and anti-migratory effects on breast cancer cells, finding three PhytoPs enhance doxorubicin's efficacy and inhibit migration.