BiophysicsbioRxiv
Nonionic surfactants can modify the thermal stability of globular and membrane proteins interfering with the thermal proteome profiling principles to identify protein targets
E. Berlin, V. Lizano-Fallas, A. Carrasco del Amor…·S. Cristobal
This paper shows that nonionic surfactants affect thermal stability of proteins, challenging thermal proteome profiling for membrane protein target identification.
DOI 10.1021/acs.analchem.2c04500