Distinct oncogenes drive distinct genome and epigenome alterations in human mammary epithelial cells
C. Fonti, A. Saumet, A. Abi-Khalil, B. Orsetti, W. Jacot, E. Cleroux, A. Bender, M. Dumas, E. Schmitt, J. Colinge, M. Weber, C. Sardet, S. du Manoir, C. Theillet
This study shows that activating different oncogenes in human mammary epithelial cells leads to distinct genetic and epigenetic changes, suggesting oncogene activation shapes breast cancer subtypes.
International Journal of Cancer · Jun 10, 2019Peer-reviewedCancer Biology