Iron Chelation Improves Ineffective Erythropoiesis and Iron Overload in Myelodysplastic Syndrome Mice
W. An, M. Feola, S. Aluri, M. Ruiz-Martinez, A. Sridharan, M. Levy, E. Fibach, X. Zhu, A. K. Verma, Y. Ginzburg
This study shows that iron chelation with deferiprone improves ineffective erythropoiesis and iron overload in MDS mice by normalizing iron metabolism and reducing oxidative stress.
bioRxiv · Oct 5, 2022Pathology