W. An

Quantifying phage infectivity from characteristics of bacterial population dynamics

This paper quantifies phage infectivity and suppression using bacterial population dynamics metrics, identifying peak density and extinction time as the most predictive.

Cbl and Cbl-b Ubiquitin Ligases are Essential for Intestinal Epithelial Stem Cell Maintenance

This study shows that Cbl and Cbl-b ubiquitin ligases are essential for intestinal epithelial stem cell maintenance by regulating the Akt-mTOR pathway.

Iron Chelation Improves Ineffective Erythropoiesis and Iron Overload in Myelodysplastic Syndrome Mice

This study shows that iron chelation with deferiprone improves ineffective erythropoiesis and iron overload in MDS mice by normalizing iron metabolism and reducing oxidative stress.

Jak2V617F Reversible Activation Shows an Essential Requirement for Jak2V617F in Myeloproliferative Neoplasms

This study shows that reversible activation of Jak2V617F in a mouse model demonstrates its essential role in myeloproliferative neoplasms and highlights the therapeutic potential of mutant-specific JAK2 inhibition.

Cryo-EM structure of yeast 90S preribosome at 3.4 Angstrom resolution

The paper presents a 3.4 Angstrom cryo-EM structure of yeast 90S preribosome, revealing new insights into the conformation of the 18S rRNA central domain.

Virus infection might cause cells producing black swimming dots

The paper investigates a virus-like pathogen associated with black swimming dots (BSDs) in cultured cells, showing it can be reisolated from BSD+ extracts-inoculated cells.

Black swimming dots in cell culture: the identity, detection method and judging criteria

The paper investigates the origin, detection, and criteria for identifying black swimming dots (BSDs) in cell culture, addressing their nature and impact on experiments.