The mechanism of motor inhibition by microtubule-associated proteins
L. S. Ferro, L. Eshun-Wilson, M. Golcuk, J. Fernandes, T. Huijben, E. Gerber, A. Jack, K. Costa, M. Gur, Q. Feng, E. Nogales, A. Yildiz
This study investigates how microtubule-associated proteins (MAPs) regulate motor protein interactions, finding that MAPs inhibit motors without blocking their binding sites and that motors must interact with MAPs to move on MAP-coated microtubules.
bioRxiv · Oct 22, 2020 · PreprintBiophysics