J. Fernandes

Torques within and outside the human spindle balance twist at anaphase

The paper investigates how molecular torques balance spindle twist during anaphase in human cells, identifying factors that increase or decrease twist.

Nanotrap Particles Improve Nanopore Sequencing of SARS-CoV-2 and Other Respiratory Viruses

The paper introduces a magnetic hydrogel particle method to improve nanopore sequencing of SARS-CoV-2 and other respiratory viruses from diagnostic samples.

A simple, inexpensive and multi scale 3D fluorescent test sample for optical sectioning microscopies

This paper introduces a simple, inexpensive 3D fluorescent test sample made from tissue paper labeled with a highlighter pen for quality control and comparison across optical sectioning microscopies.

Hybrid multisite silicon neural probe with integrated flexible connector for interchangeable packaging

This paper develops a hybrid multisite silicon neural probe with an integrated flexible connector for interchangeable packaging, demonstrating high-quality in vivo electrophysiological recordings.

The mechanism of motor inhibition by microtubule-associated proteins

This study investigates how microtubule-associated proteins (MAPs) regulate motor protein interactions, finding that MAPs inhibit motors without blocking their binding sites and that motors must interact with MAPs to move on MAP-coated microtubules.

SARS-CoV-2 infection damages airway motile cilia and impairs mucociliary clearance

This study shows SARS-CoV-2 infection damages airway motile cilia and impairs mucociliary clearance, potentially facilitating viral spread to the deeper lung.

Breast tumor-associated metalloproteases restrict reovirus oncolysis by cleaving the σ1 cell-attachment protein, and can be overcome by mutation of σ1

This study shows that breast tumor-associated metalloproteases cleave reovirus σ1 protein, reducing infectivity, and demonstrates that a σ1 mutation can overcome this inactivation.

Low-dose cadmium potentiates lung inflammatory response to 2009 pandemic H1N1 influenza virus in mice

This study shows that low-dose cadmium exposure in mice increases lung inflammation and genetic responses to H1N1 influenza virus infection.

Succession of embryonic and intestinal bacterial communities of Atlantic salmon

This study examines the succession of bacterial communities in Atlantic salmon from embryonic to intestinal stages, finding that hatching and seawater transfer significantly impact diversity and composition.