Author

E. Gottwein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

M. Manzano· 3 shared A. Patil· 1 shared E. T. Bartom· 1 shared K. Chung· 1 shared K. Morrison· 1 shared M. J. Schipma· 1 shared N. Kuehnle· 1 shared S. M. Osborne· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 17 mutual co-author links

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3 shared papersMicrobiology

M. Manzano

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CRISPR Screens Identify Novel Regulators of cFLIP Dependency and Ligand-Independent, TRAIL-R1-Mediated Cell Death

N. Kuehnle, S. M. Osborne, Z. Liang, M. Manzano, E. Gottwein

The paper identifies novel regulators of cFLIP dependency and ligand-independent TRAIL-R1-mediated cell death in PEL cells using CRISPR screens and functional experiments.

bioRxiv · Aug 17, 2022Microbiology

The oncogenic Kaposi sarcoma-associated herpesvirus encodes a mimic of the tumor suppressive miR-15/16 miRNA family

K. Morrison, M. Manzano, K. Chung, M. J. Schipma, E. T. Bartom, E. Gottwein

This study identifies KSHV miR-K6-5p as a functional mimic of the tumor suppressive miR-15/16 family, showing it inhibits cell cycle progression and promotes growth in KSHV-transformed B cells.

bioRxiv · Jun 5, 2019Microbiology

Genome-wide CRISPR Screens Reveal Genetic Mediators of Cereblon Modulator Toxicity in Primary Effusion Lymphoma

A. Patil, M. Manzano, E. Gottwein

The paper uses CRISPR screens to identify genetic mediators of cereblon modulator toxicity in primary effusion lymphoma, finding that CRBN and UBE2G1 inactivation confer resistance to different CMs.

bioRxiv · Apr 25, 2019Cancer Biology