Uncovering strain- and age-dependent differences in innate immune response to SARS-CoV-2 infection in nasal epithelia using 10X single-cell sequencing
J. J.-Y. Chang, S. Grimley, B. Tran, G. Deliyannis, C. Tumpach, E. J. Steinig, S. L. Wong, S. A. Waters, T. P. Stinear, M. E. Pitt, D. F. J. Purcell, E. Vincan, L. J. M. Coin
The paper uses single-cell sequencing to compare innate immune responses to SARS-CoV-2 in nasal epithelial cells from adults and adolescents, finding age- and strain-dependent differences.
bioRxiv · Mar 4, 2023 · PreprintImmunology