Author
D. F. J. Purcell
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2018-2023 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 18 mutual co-author links5 papers
Recent·Most cited
- DOI 10.1016/j.omtm.2024.101380
- ImmunologybioRxivPreprint
Uncovering strain- and age-dependent differences in innate immune response to SARS-CoV-2 infection in nasal epithelia using 10X single-cell sequencing
J. J.-Y. Chang, S. Grimley, B. Tran…·L. J. M. Coin
The paper uses single-cell sequencing to compare innate immune responses to SARS-CoV-2 in nasal epithelial cells from adults and adolescents, finding age- and strain-dependent differences.
- BiochemistrybioRxivPreprint
SARS-CoV-2 Spike receptor-binding domain with a G485R mutation in complex with human ACE2
C. M. Weekley, D. F. J. Purcell, M. W. Parker
This study reports the crystal structure of SARS-CoV-2 Spike RBD with a G485R mutation bound to human ACE2, showing structural changes that may affect antigenic escape.
DOI 10.1101/2021.03.16.434488 - MicrobiologybioRxiv
Transcriptional and epi-transcriptional dynamics of SARS-CoV-2 during cellular infection
J. J.- Y. Chang, D. Rawlinson, M. E. Pitt…·L. J. M. Coin
This study examines SARS-CoV-2 transcriptional and epi-transcriptional dynamics using long-read sequencing in human and primate infection models, revealing distinct patterns of sgRNA regulation and modification.
DOI 10.1016/j.celrep.2021.109108 - MicrobiologybioRxiv
A Multiplex Droplet Digital PCR Assay for Quantification of HTLV-1c DNA Proviral Load and T-Cells from Blood and Respiratory Exudates Sampled in a Remote Setting
D. Yurick, G. Khoury, B. Clemens…·D. F. J. Purcell
This study validates a duplex ddPCR assay to quantify HTLV-1c proviral load and T-cells in remote Indigenous Australian samples, comparing results to flow cytometry.
DOI 10.1128/jcm.01063-18