The Implant-Induced Foreign Body Response is Limited by CD13-Dependent Regulation of Ubiquitination of Fusogenic Proteins
M. Ghosh, F. McGurk, R. Norris, A. Dong, S. Nair, E. Jellison, P. A. Murphy, R. Verma, L. H. Shapiro
This study shows CD13 regulates macrophage fusion by controlling ubiquitination of fusogenic proteins, limiting foreign body response fibrosis and suggesting CD13 as a therapeutic target.
The Journal of Immunology · Dec 27, 2023Peer-reviewedCell Biology