Evolutionary BiologybioRxiv
Identification and evolution of Cas9 tracrRNAs
S. K. Dooley, E. K. Baken, W. Moss…·J. K. Young
The paper presents a bioinformatic method to identify Cas9 tracrRNAs using sequence homology and secondary structure, revealing evolutionary conservation of their structure across Cas9 lineages.
DOI 10.1089/crispr.2020.0093