Cell BiologybioRxiv
A protease-initiated model of wound detection
J. T. O'Connor, A. C. Stevens, E. K. Shannon…·A. Page-McCaw
The paper identifies a protease-initiated signal transduction pathway that enables epithelial cells to detect wounds through the activation of Gbp ligands and Mthl10 receptors, leading to calcium release.
DOI 10.1016/j.devcel.2021.06.020