Author

E. Kuroda

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

K. J. Ishii· 2 shared T. Hayashi· 2 shared A. Kumanogoh· 1 shared A. Sood· 1 shared A. Yamamoto· 1 shared B. Temizoz· 1 shared C. Coban· 1 shared C. Nakai· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

K. J. Ishii

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3 papers

Recent·Most cited

5,6-dimethylxanthenone-4-acetic acid (DMXAA), a Partial STING Agonist, Competes for Human STING Activation

B. Temizoz, T. Shibahara, K. Hioki, T. Hayashi, K. Kobiyama, M. S. J. Lee, N. Surucu, E. Sag, A. Kumanogoh, M. Yamamoto, M. Gursel, S. Ozen, E. Kuroda, C. Coban, K. J. Ishii

This paper investigates DMXAA's partial STING agonist activity and develops HHMX, a derivative that antagonizes STING-mediated immune responses in both humans and mice.

bioRxiv · Dec 7, 2023 · PreprintImmunology

A stress sensor IRE1α is required for bacterial exotoxin-induced inflammasome activation in tissue-resident macrophages

I. Sasaki, Y. Fukuda-Ohta, C. Nakai, N. Wakaki-Nishiyama, C. Okamoto, T. Orimo, D. Okuzaki, S. Morita, S. Kaji, Y. Furuta, H. Hemmi, T. Kato, A. Yamamoto, T. Tanaka, K. Hoshino, , T. Kaisho

The paper shows that IRE1α is essential for CTB and CT-induced IL-1β production in tissue-resident macrophages via NLRP3 and pyrin inflammasomes.

bioRxiv · Jul 6, 2023 · PreprintImmunology

Helicobacter small RNA regulates host adaptation and carcinogenesis

R. Kinoshita-Daitoku, K. Kiga, R. Otsubo, Y. Ogura, T. Sanada, Z. Bo, T. V. Phuoc, T. Okano, T. Iida, R. Yokomori, E. Kuroda, S. Hirukawa, M. Tanaka, A. Sood, P. Subsomwong, , H. Mimuro

This study identifies HPnc4160, a small RNA in H. pylori, that negatively regulates host adaptation and gastric cancer by modulating gene expression and bacterial colonization.

bioRxiv · Feb 15, 2020 · PreprintMicrobiology