E. L. Huttlin

Altered glutamine metabolism of cultured fibroblasts predicts severity of cardiac dysfunction in the dilated cardiomyopathy with ataxia syndrome (DCMA), a mitochondrial cardiomyopathy

The paper identifies altered glutamine and lactate metabolism in DCMA patient fibroblasts as a predictor of cardiac dysfunction severity.

Full-featured, real-time database searching platform enables fast and accurate multiplexed quantitative proteomics.

The paper introduces a real-time database search platform, Orbiter, that improves the efficiency and accuracy of multiplexed quantitative proteomics by reducing data acquisition time and increasing protein quantification.