Cryo-EM structure and functional landscape of an RNA polymerase ribozyme
E. K. S. McRae, C. J. K. Wan, E. L. Kristoffersen, K. Hansen, E. Gianni, I. Gallego, J. F. Curran, J. Attwater, P. Holliger, E. S. Andersen
The paper determines the cryo-EM structure of a triplet polymerase ribozyme and maps its functional landscape using mutation analysis.
bioRxiv · Aug 23, 2022Biochemistry