Cell BiologybioRxiv
TANGO2-related rhabdomyolysis symptoms are associated with abnormal autophagy functioning
H. de Calbiac, S. Montealegre, M. Straube…·P. de Lonlay
This study shows TANGO2 mutations impair autophagy, leading to rhabdomyolysis, and calpeptin treatment can rescue autophagy and locomotor defects in zebrafish models.
DOI 10.1080/27694127.2024.2306766