Targeting Damaged Collagen for Intra-Articular Delivery of Therapeutics using Collagen Hybridizing Peptides
E. Luke, P. Ratnatilaka Na Bhuket, S. M. Yu, J. A. Weiss
This study shows collagen hybridizing peptides (CHPs) extend the retention time of near-infrared fluorophores in rat knee joints by binding to collagen, with greater signal in osteoarthritis joints.
bioRxiv · Dec 6, 2022Bioengineering