Assessing the impact of autologous neutralizing antibodies on rebound dynamics in postnatally SHIV-infected ART-treated infant Rhesus macaques
E. Mainou, S. Berendam, V. Obregon-Perko, E. Uffman, C. Phan, G. Shaw, K. Bar, M. Kumar, E. Fray, J. Siliciano, R. Siliciano, G. Silvestri, S. Permar, G. Fouda, J. McCarthy, , J. M. Conway
This study examines how early ART initiation in HIV-infected infants affects antibody development and latent reservoir dynamics, showing their opposing impacts on post-treatment viral rebound.
bioRxiv · Jun 1, 2024 · PreprintImmunology