IL-6 prevents Th2 cell polarization by promoting SOCS3-dependent suppression of IL-2 signaling
H. Bachus, E. McLaughlin, C. Lewis, A. M. Papillion, E. N. Benveniste, D. D. Hill, A. F. Rosenberg, A. Ballesteros-Tato, B. Leon
This study shows IL-6 prevents Th2 cell polarization by suppressing IL-2 signaling through SOCS3, reducing allergic inflammation and IgE response.
bioRxiv · Dec 5, 2022Immunology