Author

A. F. Rosenberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 7 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Assay:proteomics· 6 Research Focus:host-pathogen & immune response· 5 Research Focus:cell type annotation· 3 Organism:human· 3 Organism:mouse· 3 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

F. E. Lund· 4 shared J. T. Killian· 3 shared R. G. King· 3 shared T. D. Randall· 3 shared B. Leon· 2 shared G. Yang· 2 shared J. Akther· 2 shared S. Qiu· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersImmunology

F. E. Lund

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Crohn's patients and healthy infants share immunodominant B cell response to commensal flagellin peptide epitopes

Q. Zhao, L. W. Duck, J. T. Killian, A. F. Rosenberg, P. J. Mannon, R. G. King, L. A. Denson, S. Kugathasan, E. N. Janoff, M. C. Jenmalm, C. O. Elson

The paper identifies a shared B cell response to a conserved flagellin epitope in Crohn's disease patients and healthy infants, suggesting a potential early failure of homeostatic immunity.

bioRxiv · Aug 8, 2023Immunology

HLA topography enforces shared and convergent immunodominant B cell and antibody alloresponses in transplant recipients

J. T. Killian, R. G. King, A. C. Lucander, J. L. Kizziah, C. F. Fucile, R. Diaz-Avalos, S. Qiu, A. Silva-Sanchez, B. J. Mousseau, K. J. Macon, A. R. Callahan, G. Yang, M. E. Hossain, J. Akther, J. A. Houp, , F. E. Lund

The paper identifies an immunodominant B cell response targeting specific HLA residues in transplant recipients, suggesting antigenic topography drives antibody-mediated rejection.

bioRxiv · Mar 31, 2023 · PreprintImmunology

A high-throughput multiplex array for antigen-specific serology with automated analysis.

A. F. Rosenberg, J. T. Killian, T. J. Green, J. Akther, E. Hossain, S. Qiu, G. Yang, T. D. Randall, F. E. Lund, R. G. King

The paper describes a high-throughput CBA system for antigen-specific serology with automated analysis tools to quantify IgM, IgA, and IgG concentrations.

bioRxiv · Mar 29, 2023 · PreprintImmunology

IL-6 prevents Th2 cell polarization by promoting SOCS3-dependent suppression of IL-2 signaling

H. Bachus, E. McLaughlin, C. Lewis, A. M. Papillion, E. N. Benveniste, D. D. Hill, A. F. Rosenberg, A. Ballesteros-Tato, B. Leon

This study shows IL-6 prevents Th2 cell polarization by suppressing IL-2 signaling through SOCS3, reducing allergic inflammation and IgE response.

bioRxiv · Dec 5, 2022Immunology

Chitinase-3-like 1 regulates TH2 cells, TFH cells and IgE following helminth infection

M. L. Curtiss, A. F. Rosenberg, C. D. Scharer, N. A. B. Benavides, J. E. Bradley, B. Leon, C. C. Steele, T. D. Randall, F. E. Lund

This study shows that ChI3L1 is required for TH2, TFH, and IgE responses following helminth infection and vaccination, but not for IgG1 responses.

bioRxiv · Sep 26, 2022 · PreprintImmunology

Mixed Origins: HIV gp120-specific memory develops from pre-existing memory and naive B cells following vaccination in humans

M. Basu, M. S. Piepenbrink, C. Fucile, C. A. Bunce, L.-X. Man, J. Liesveld, A. F. Rosenberg, M. C. Keefer, J. J. Kobie

This study shows that HIV gp120-specific memory B cells arise from both naive and pre-existing cross-reactive memory B cells following vaccination.

bioRxiv · Sep 1, 2021Immunology

A Non-redundant Role for T cell-derived IL-22 in Antibacterial Defense of Colonic Crypts

C. T. Weaver, C. L. Zindl, S. J. Witte, V. A. Laufer, M. Gao, Z. Yue, D. J. Silberger, S. N. Harbour, J. R. Singer, D. Pham, C. E. Moseley, B. Cai, H. Turner, F. E. Lund, B. A. Vallance, , R. D. Hatton

This study shows that T cell-derived IL-22 is essential for antibacterial defense and damage control in intestinal crypts, despite ongoing ILC3-derived IL-22 production.

bioRxiv · May 11, 2021 · PreprintImmunology

Complex responses to inflammatory oxidants by the probiotic bacterium Lactobacillus reuteri

P. Basu Thakur, A. R. Long, B. J. Nelson, R. Kumar, A. F. Rosenberg, M. J. Gray

This study examines how Lactobacillus reuteri responds to inflammatory oxidants like H2O2 and HOCl, identifying unique resistance mechanisms that could inform microbiota-targeted therapies for gut inflammation.

bioRxiv · Apr 11, 2019 · PreprintMicrobiology