GTP-dependent formation of straight oligomers leads to nucleation of microtubules
R. Ayukawa, S. Iwata, H. Imai, S. Kamimura, M. Hayashi, K. X. Ngo, I. Minoura, S. Uchimura, T. Makino, M. Shirouzu, H. Shigematsu, K. Sekimoto, B. Gigant, E. Muto
The paper shows that GTP-dependent formation of straight oligomers is essential for microtubule nucleation, with a mutation increasing straight oligomers and accelerating nucleation.
Journal of Cell Biology · Feb 5, 2021Peer-reviewedBiophysics