Stromal Hedgehog pathway activation by IHH suppresses lung adenocarcinoma growth and metastasis by limiting reactive oxygen species
S. Kasiri, B. Chen, A. N. Wilson, A. Reczek, S. Mazambani, J. Gadhvi, E. Noel, U. Marriam, B. Mino, W. Lu, L. Girard, L. Solis, K. Luby-Phelps, J. Bishop, J.-W. Kim, J. Kim
This study shows that IHH activates the stromal Hedgehog pathway to suppress lung adenocarcinoma growth and metastasis by reducing reactive oxygen species.
bioRxiv · Aug 27, 2019Cancer Biology