In vivo quantitative high-throughput screening for drug discovery and comparative toxicology
J. Inglese, P. Dranchak, E. Oliphant, B. Queme, L. Lamy, Y. Wang, R. Huang, M. Xia, D. Tao
This paper describes an in vivo qHTS method using C. elegans to assess drug toxicity and therapeutic potential, demonstrating its feasibility with anti-infective agents and toxicological compounds.
bioRxiv · Aug 26, 2022Pharmacology & Toxicology