BiochemistrybioRxivPreprint
Repurposing host-guest chemistry to sequester virulence and eradicate biofilms in multidrug resistant Pseudomonas aeruginosa and Acinetobacter baumannii
C. Jonkergouw, N. K. Beyeh, E. Osmekhina…·M. B. Linder
This paper identifies Pillar[5]arene, a synthetic macrocycle that targets virulence factors in multidrug-resistant bacteria, reducing biofilms and enhancing antibiotic efficacy.
DOI 10.1101/2023.03.01.530582