All-optical electrophysiology refines populations of in silico human iPS-CMs for drug evaluation
M. Paci, E. Passini, A. Klimas, S. Severi, J. Hyttinen, B. Rodriguez, E. Entcheva
This paper combines all-optical electrophysiology with in silico models to refine human hiPS-CMs for drug evaluation, showing accurate prediction of drug effects and adverse events.
bioRxiv · Oct 9, 2019Pharmacology & Toxicology