Interleukin-1 receptor antagonist is a conserved factor for exacerbating tuberculosis susceptibility
O. V. Lee, E. Pathak, S. Hernandez-Bazan, D. X. Ji, B. A. Rosa, D. L. Jaye, S. Suliman, M. Mitreva, C. Gabay, R. E. Vance, D. I. Kotov
The paper identifies IL-1 receptor antagonist as a conserved factor limiting Mtb control across mice, non-human primates, and humans.
bioRxiv · Oct 27, 2023 · PreprintImmunology