Author

D. L. Jaye

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Pathology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Research Focus:differential expression· 3 Organism:human· 3 Approach:deep learning· 2 Approach:experimental assay· 2 Organism:mouse· 2 Organism:non-human primate· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

D. I. Kotov· 2 shared J. E. Lewis· 2 shared L. A. D. Cooper· 2 shared O. V. Lee· 2 shared R. E. Vance· 2 shared A. Aljudi· 1 shared A. Khanna· 1 shared A. Moon· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

D. I. Kotov

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Author profile →

4 papers

Recent·Most cited

Automated Deep Learning-Based Diagnosis and Molecular Characterization of Acute Myeloid Leukemia using Flow Cytometry

J. E. Lewis, L. A. D. Cooper, D. L. Jaye, O. Pozdnyakova

This paper develops a deep learning pipeline for automated AML diagnosis and molecular characterization using flow cytometry data, achieving high accuracy in classification and variant prediction.

Modern Pathology · Jan 1, 2024Peer-reviewedPathology

Interleukin-1 receptor antagonist is a conserved factor for exacerbating tuberculosis susceptibility

O. V. Lee, E. Pathak, S. Hernandez-Bazan, D. X. Ji, B. A. Rosa, D. L. Jaye, S. Suliman, M. Mitreva, C. Gabay, R. E. Vance, D. I. Kotov

The paper identifies IL-1 receptor antagonist as a conserved factor limiting Mtb control across mice, non-human primates, and humans.

bioRxiv · Oct 27, 2023 · PreprintImmunology

Early cellular mechanism of type I interferon-driven susceptibility to tuberculosis

D. I. Kotov, O. V. Lee, S. A. Fattinger, C. Langner, J. V. Guillen, J. M. Peters, A. Moon, E. M. Burd, K. C. Witt, D. B. Stetson, D. L. Jaye, B. D. Bryson, R. E. Vance

This study identifies interstitial macrophages and plasmacytoid dendritic cells as key producers of type I IFN during Mtb infection, showing their role in driving tuberculosis pathogenesis through IFN-driven mechanisms.

bioRxiv · Oct 6, 2022Immunology

An Automated Pipeline for Differential Cell Counts on Whole-Slide Bone Marrow Aspirate Smears

J. E. Lewis, C. W. Shebelut, B. R. Drumheller, X. Zhang, N. Shanmugam, M. Attieh, M. C. Horwath, A. Khanna, G. H. Smith, D. A. Gutman, A. Aljudi, L. A. D. Cooper, D. L. Jaye

This paper develops an automated machine learning pipeline for differential cell counts on whole-slide bone marrow aspirate smears, showing high concordance with manual counts and reduced intra-slide variance.

bioRxiv · May 26, 2022Pathology