The defined TLR3 agonist, Nexavant, exhibits anti-cancer efficacy and potentiates anti-PD-1 antibody therapy by enhancing immune cell infiltration.
D. Kim, S.-H. Lee, Y.-H. Choi, S.-M. Kang, M.-G. L. Lee, S.-B. Hong, E. Perouzel, A. Debin
This paper evaluates Nexavant, a TLR3 agonist, showing enhanced anti-cancer effects and synergy with anti-PD-1 therapy through immune cell infiltration.
bioRxiv · Oct 25, 2023Immunology