The human-restricted oncoprotein POU5F1B enhances cell invasiveness through plasma membrane remodeling
S. Offner, L. Abrami, E. Burri, A. Mery, B. Drake, J. Shi, E. M. Unterauer, J. Duc, E. Planet, R. Jungmann, A. Reymond, G. Fantner, M. S. Sakar, B. Wehrle-Haller, G. van der Goot, , L. Simo Riudalbas
This study identifies POU5F1B as a human-specific oncoprotein that enhances cell invasiveness via plasma membrane remodeling through ubiquitination and S-acylation.
bioRxiv · Oct 30, 2023 · PreprintCancer Biology