The long non-coding RNA lnc-HLX-2-7 is oncogenic in group 3 medulloblastomas
K. Katsushima, B. Lee, H. Kunhiraman, C. Zhong, R. Murath, J. Ying, B. Liu, A. Garancher, H. L. Monforte, I. Gonzalez-Gomez, S. Stapleton, R. Vibhakar, C. Bettegowda, R. J. Wechsler-Reya, G. Jallo, , R. J. Perera
This study identifies lnc-HLX-2-7 as an oncogenic lncRNA in group 3 medulloblastomas, showing it promotes tumor growth and is regulated by MYC and JQ1.
bioRxiv · Jun 8, 2020Cancer Biology